2-(4-((2-ethyl-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)methyl)phenyl)-5-(piperidin-4-yl)-1,3,4-oxadiazole
NE 52-QQ57
CAS: 1401728-56-0
Molecular Formula: C24H28N6O
2-(4-((2-ethyl-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)methyl)phenyl)-5-(piperidin-4-yl)-1,3,4-oxadiazole - Names and Identifiers
2-(4-((2-ethyl-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)methyl)phenyl)-5-(piperidin-4-yl)-1,3,4-oxadiazole - Physico-chemical Properties
| Molecular Formula | C24H28N6O |
| Molar Mass | 416.52 |
| Density | 1.32±0.1 g/cm3(Predicted) |
| pKa | 9.56±0.10(Predicted) |
| Storage Condition | -20°C |
| Use | NE 52-QQ57 is a selective, orally active GPR4 antagonist with an IC50 of 70 nM. NE 52-QQ57 has anti-inflammatory activity. |
2-(4-((2-ethyl-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)methyl)phenyl)-5-(piperidin-4-yl)-1,3,4-oxadiazole - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.401 ml | 12.004 ml | 24.008 ml |
| 5 mM | 0.48 ml | 2.401 ml | 4.802 ml |
| 10 mM | 0.24 ml | 1.2 ml | 2.401 ml |
| 5 mM | 0.048 ml | 0.24 ml | 0.48 ml |
Last Update：2024-01-02 23:10:35
2-(4-((2-ethyl-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)methyl)phenyl)-5-(piperidin-4-yl)-1,3,4-oxadiazole - Introduction
NE 52-QQ57 is a high molecular compound, which belongs to Polyether ketone material. It has high heat resistance, chemical resistance and mechanical strength. NE 52-QQ57 is commonly used in the preparation of high temperature, corrosion-resistant seals, valves and pipes.
NE 52-QQ57 is prepared by polymerization. Specifically, first, an appropriate amount of epoxy cycloalkanone and epoxy resin are mixed in a certain ratio, and then an appropriate amount of polyether ether ketone mixture is added for reaction. During the reaction, a certain temperature and catalyst are required. Finally, the Polyether ketone material NE 52-QQ57 was obtained.
In terms of safety information, NE 52-QQ57 is a material with high chemical stability and good corrosion resistance to general chemicals. However, care needs to be taken during the preparation process to prevent contact with the skin and eyes, and to ensure good ventilation to avoid inhalation of harmful gases. During use, avoid exposure to open flames and high temperature environments to prevent them from decomposing or burning to produce harmful substances. In addition, the material needs to be stored and handled properly in accordance with local safe operation guidelines and regulations. In the event of an accident, immediately take appropriate first aid measures and consult a professional to deal with it.
NE 52-QQ57 is prepared by polymerization. Specifically, first, an appropriate amount of epoxy cycloalkanone and epoxy resin are mixed in a certain ratio, and then an appropriate amount of polyether ether ketone mixture is added for reaction. During the reaction, a certain temperature and catalyst are required. Finally, the Polyether ketone material NE 52-QQ57 was obtained.
In terms of safety information, NE 52-QQ57 is a material with high chemical stability and good corrosion resistance to general chemicals. However, care needs to be taken during the preparation process to prevent contact with the skin and eyes, and to ensure good ventilation to avoid inhalation of harmful gases. During use, avoid exposure to open flames and high temperature environments to prevent them from decomposing or burning to produce harmful substances. In addition, the material needs to be stored and handled properly in accordance with local safe operation guidelines and regulations. In the event of an accident, immediately take appropriate first aid measures and consult a professional to deal with it.
Last Update：2024-04-09 21:53:21
![2-(4-((2-ethyl-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)methyl)phenyl)-5-(piperidin-4-yl)-1,3,4-oxadiazole](http://res.chembk.com/assets/images/structure/184515.png)
Supplier List
View History